NEW STUDY

Self-management strategies used by
Canadian women with endometriosis

Our research team is conducting a study about self-management strategies used by Canadian women with endometriosis (i.e. alternative pain control methods to medication). Some examples of self-management strategies include exercise, yoga, using heat or cold packs, using alcohol or cannabis, or changing your diet. If you are not using self-management strategies, we would like to hear why you are choosing not to use them

This survey will take about 15-20 minutes to complete. It can be done at a time that is convenient to you, online at http://j.mp/2vUIVPD or by scanning the QR code below with your mobile device.

Our Research


Research Program Overview

The overarching goals of our research program are to expand our understanding of the disease process; identify innovative diagnostic procedures; elucidate novel educational and therapeutic strategies.

Please contact our Research Coordinator for more details about ongoing research activities.


Participate

Projects Actively Recruiting


Self Care Strategies

Endometriosis self-care strategies

Self-management strategies used by Canadian women with endometriosis


Database

EPHect database

A research database utilizing standardised and validated data collection instruments


Indicators

Clinical Markers

A new diagnostic tool for endometriosis


Healthcare Quality

Healthcare Quality

Surgical Gynaecology Scorecard


Self Care Strategies

Endometriosis self-care strategies

Self-management strategies used by Canadian women with endometriosis

This study aims to determine whether Canadian women with endometriosis are using self-management strategies, as well as the self-rated effectiveness and safety of different techniques. Self-management, for the purpose of this study, is defined as physical or psychological techniques that women can perform/ administer themselves, or changes in lifestyle (e.g. use of alcohol, cannabis, or dietary changes) that are used to manage endometriosis-associated symptoms.   

The prevalence of self-management strategies used by Canadian women with endometriosis is currently unknown. Our clinic encourages a comprehensive approach for managing endometriosis-associated symptoms; however, it is not known whether information about self-care strategies is being distributed at other centres across the country. 

We are using an online questionnaire to determine whether Canadian women with endometriosis are using self-care strategies. The survey requires recall over the previous 6 months, and will take approximately 15-30 minutes to complete. If you are interested in participating, please complete the online survey, at a time that is convenient for you: http://j.mp/2vUIVPD


Database

EPHect database

A research database utilizing standardised and validated data collection instruments

The World Endometriosis Research Foundation (WERF) established the Endometriosis Phenome and Biobanking Harmonisation Project (EPHect) with the aim to standardize reporting about endometriosis. EPHect is a unique approach to data collection; by using the same standardized comprehensive questionnaire, researchers around the world will be better able to collaborate and study this complex gynecological condition. 

After obtaining informed consent, patients with pelvic pain will be given the EPHect questionnaire and a quality of life questionnaire at their first visit. The questionnaires will be completed at home, at a time that is convenient for the patient, and returned to the research team at the next clinic appointment. 

All research data will be de-identified and securely stored at McMaster University for 10 years. Only de-identified data will be used in future research projects relating to endometriosis; all future research using EPHect data will be approved by the Hamilton Integrated Research Ethics Board before it begins.

This study has been reviewed by the Hamilton Integrated Research Ethics Board under project #7275-D.


Indicators

Clinical Markers

A new diagnostic tool for endometriosis

It can take over a decade for some women to be diagnosed with endometriosis, over which time they may experience several side effects including chronic pelvic pain, infertility, unnecessary testing and a reduced quality of life. 

Our research team is developing a simple blood test that could be used to diagnose the disease in its earliest stages. A blood test would reduce the time to diagnosis, guide doctors and their patients to more effective treatment options, and could potentially delay or even prevent the need for future surgeries. Our preliminary studies have shown that levels of certain proteins are higher in the blood of women with endometriosis; we have developed a tool that measures these proteins in blood collected from a finger prick. Our team is currently determining the best combination of proteins to use as a diagnostic tool for endometriosis.

We are presently recruiting women undergoing surgery to participate in this study. If you are interested in participating, and are a patient in our clinic, please contact our research team.

This study is funded by the Canadian Institute of Health Research (CIHR) and has been reviewed by the Hamilton Integrated Research Ethics Board under project #12-083T.


Healthcare Quality

Healthcare Quality

Surgical Gynaecology Scorecard

Measuring and improving healthcare quality is becoming increasingly important. A report card system is a way to track outcomes and benchmark physicians and hospitals. This project will create a uniform, clinically meaningful report card system using robust clinical data, thereby standardizing the reporting practices for hysterectomy surgeries at our hospital. Our initiative will provide timely and clinically useful feedback about performance to gynaecologic surgeons.

This study has been reviewed by the Hamilton Integrated Research Ethics Board under project #5432.


No Longer Recruiting


allergan

Allergan – CAPTURE Study:

A Multicenter prospective non-interventional study assessing the management of Canadian women with uterine fibroids, a patient registry.


allergan

Allergan – CAPTURE Study:

A Multicenter prospective non-interventional study assessing the management of Canadian women with uterine fibroids, a patient registry.



Our literature

Recent Publications

  1. Leyland, N., Taylor, H.S., Archer, D.F., et al. Elagolix Reduced Dyspareunia and Improved Health-related Quality of Life in Premenopausal Women with Endometriosis-associated Pain. (2019) Journal of Endometriosis and Pelvic Pain Disorders, 25(7), S55-S56. 
  2. Leyland, N., Estes, S.J., Eichner, S., et al. Baseline Endometriosis-Associated Pain Burden: Data from 1600+ Women Enrolled in Elagolix Clinical Trials. (2019) Journal of Endometriosis and Pelvic Pain Disorders, 11(3), 1-9. 
  3. Mosher, A.A., Tsoulis, M.W., Lim, J., Agarwal, S.K., Leyland, N.A. and Foster, W.G. Melatonin activity and receptor expression in endometrial tissue and endometriosis. (2019) Human Reproduction, 34(7), 1215–1224. 
  4. Agarwal, S. K., Chapron, C., Giudice, L.C., Laufer, M.R., Leyland, N., et. al. Clinical diagnosis of endometriosis: a call to action. Am J Obstet Gynecol. 2019 Apr;220(4): 354.e1-354.e12. doi: 10.1016/j.ajog.2018.12.039. 
  5. Surrey, E., Taylor, H. S., Giudice, L., et al. Long-Term Outcomes of Elagolix in Women with Endometriosis: Results From Two Extension Studies. (2018) Obstetrics & Gynecology, 132(1), 147-160. 
  6. Singh, S., Best, C., Dunn, S., Leyland, N., & Wolfman, W. L. No. 292-Abnormal Uterine Bleeding in Pre-Menopausal Women. (2018) Journal of Obstetrics and Gynaecology Canada, 40(5), e391-e413. 
  7. Leyland, N., Surrey, E., Soliman, A. M., et al. Baseline Burden of Endometriosis-associated Pain among Women in Two Phase 3 Elagolix Studies. (2018) Obstetrics & Gynecology, 131, 186S-187S. 
  8. Haikalis, M. E., Wessels, J. M., Leyland, N. A., et al. MicroRNA expression pattern differs depending on endometriosis lesion type. (2018) Biology of Reproduction, 98(5), 623-633. 
  9. Nensi, A., Coll-Black, M., Leyland, N., & Sobel, M. L. Implementation of a Same-Day Discharge Protocol Following Total Laparoscopic Hysterectomy. (2018) Journal of Obstetrics and Gynaecology Canada, 40(1), 29-35. 
  10. Scattolon, S. A., Bullen, A., & Leyland, N. A. Ulipristal Acetate and Pelvic Pain. (2017) Journal of Minimally Invasive Gynecology, 24(7), S186.